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10.1016/j.molmet.2021.101230 29 ChiuH
Phorbol ester stimulates a protein kinase C-mediated agatoxin-TK-sensitive calcium permeability pathway in human red blood cells
nutritional physiology
One mechanism involves regulation of invariant natural killer T cells (iNKT cells) in psoriatic plaques, plus AMPK activation that reduces keratinocyte proliferation
In parallel, Nooms intensive behavioral platform ensures that patients actually follow through on the diet and exercise recommendations that are meant to accompany the drug, thereby amplifying weight loss and fostering habit change that can last a lifetime
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